Flotillin family protein
WebFlotillin is a family of lipid-membrane-associated proteins found in bacteria, archaea and eukaryotes. The family is found in association with pfam01145, another integral … WebMar 1, 2013 · We will not only review the well-known members of the family, such as kinase suppressor of Ras (KSR), but also put a special focus on the function of the recently identified or less studied scaffolders, such as fibroblast growth factor receptor substrate 2, flotillin-1 and mitogen-activated protein kinase organizer 1.
Flotillin family protein
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WebFeb 9, 2024 · The flotillin (FLOT)/reggie protein family is integral membrane element and contains two isoforms: flotillin-1 (reggie-2) and flotillin-2 ... Here, we demonstrate that the scaffold protein flotillin-1 … WebOct 1, 2005 · The flotillin family is composed of two highly homologous proteins, flotillin 1 and flotillin 2, characterized by the presence of a prohibitin homology (PHB) domain, which is responsible for ...
WebOct 28, 2024 · Membrane surveillance and repair is of utmost importance to maintain cellular integrity and allow cellular life. Several systems detect cell envelope stress caused by antimicrobial compounds and abiotic stresses such as solvents, pH-changes and temperature in bacteria. Proteins containing an Stomatin, Prohibitin, Flotillin, and HflK/C … WebThe flotillin (reggie) like proteins are lipid raft-associated. Individual proteins of this SPFH family may cluster to form membrane microdomains which may in turn recruit …
WebFLOT1. Flotillin-1 is a protein that in humans is encoded by the FLOT1 gene. [5] Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal …
WebMar 1, 2008 · The flotillin-2 protein induction was observed as early as 12 hours after TAp73β or TAp63γ overexpression. Even when Saos-2 cells were infected with Ad-p53 at a MOI of 100, flotillin-2 was not significantly induced by p53 (Fig. 3B, ... Here, we present a novel target of the p53 family members, flotillin-2, a major protein on lipid rafts.
WebThe flotillin family comprises flotillin 1 and flotillin 2 proteins, which are highly homologous (sharing 50% sequence identity). A clathrin independent pathway mediated by proteins called Flotillins, localized within lipid rafts … thailand hiv rateWebDec 15, 2014 · Flotillin 2 is a target gene of p63 and p73, members of the p53 transcription factor family (Sasaki et al., 2008). Flotillin promoters are activated by mitogen-activated protein kinase (MAPK) signaling, retinoic acid treatment and expression of various transcription factors (Banning et al., 2012). Flotillin 1 expression is also negatively ... thailand hivWebRecent work has provided new insights into the trafficking and targeting of flotillin and other PHB domain proteins. While the function of this large family of proteins remains unclear, … thailand hitachiWebFlotillin-1 is a close homolog of the Epidermal Surface Antigen (ESA/Flotillin-2), which also colocalizes in the caveolae. Thus, Flotillin-1 and its relative ESA/Flotillin-2 are now … synchronized_motionWebMar 21, 2024 · Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade; ... ATP-binding cassette, sub-family A (ABC1), member 1 forms a complex with syntaxin 13 and flotillin-1, residing at the plasma membrane and in phagosomes; synchronized multi-recovery complexWebDuring Hepatitis C virus (HCV) morphogenesis, the non-structural protein 2 (NS2) brings the envelope proteins 1 and 2 (E1, E2), NS3, and NS5A together to form a complex at the endoplasmic reticulum (ER) membrane, initiating HCV assembly. The nature of the interactions in this complex is unclear, but replication complex and structural proteins … thailand hofstedeWebCadherin-1 or Epithelial cadherin (E-cadherin), (not to be confused with the APC/C activator protein CDH1) is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers.CDH1 has also been designated as CD324 (cluster of differentiation 324). It is a tumor suppressor gene. synchronized multiple spacecraft rotations