Graphical multiple testing procedure
WebIn the recent past multiple test procedures have been developed that reflect the relative importance of different study objectives, such as fixed sequence, fallback, and gatekeeping procedures. In addition, graphical approaches have been proposed that facilitate the visualization and communication of Bonferroni-based closed test procedures for ... Web16 rows · Aug 12, 2011 · Using graphical approaches, one can explore different test strategies together with the clinical ...
Graphical multiple testing procedure
Did you know?
WebDec 30, 2014 · Accordingly, a variety of multiple test procedures exist for pharmaceutical trial applications, which are typically defined on a single structured family of null hypotheses. For some confirmatory clinical trials with multiple objectives, however, it is advantageous to address the arising multiplicity problems via grouped families of hypotheses. WebDec 1, 2024 · In many large scale multiple testing applications, the hypotheses often have a known graphical structure, such as gene ontology in gene expression data. Exploiting …
WebDec 2, 2008 · We propose a simple iterative graphical approach to construct and perform such Bonferroni-type tests. The resulting multiple test procedures are represented by directed, weighted graphs, where each node corresponds to an elementary hypothesis, together with a simple algorithm to generate such graphs while sequentially testing the … WebBiometrics, Boehringer-Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA Many multiple testing procedures (MTP) have been developed in recent years. Among these new …
WebThe confirmatory analysis of pre-specified multiple hypotheses has become common in pivotal clinical trials. In the recent past multiple test procedures have been developed that reflect the ... WebLarge-scale multiple testing tasks often exhibit dependence. Leveraging the dependence between individual tests is still one challenging and impor-tant problem in statistics. With recent advances in graphical models, it is fea-sible to use them to capture the dependence among multiple hypotheses. We propose a multiple testing procedure which is ...
WebJan 1, 2015 · In addition, graphical approaches have been proposed that facilitate the visualization and communication of Bonferroni-based closed test procedures for common multiple test problems, such as ...
WebMar 16, 2024 · A graphical multiple test procedure was proposed for group sequential trials using weighted Bonferroni test. In this paper, we extend the framework for the … chin grabWebJan 27, 2024 · Abstract:In recent years, graphical multiple testing procedures have gained popularity due to their generality and ease of interpretation. In contemporary … granite and marble services pipertonWebIn statistics, the multiple comparisons, multiplicity or multiple testing problem occurs when one considers a set of statistical inferences simultaneously or infers a subset of parameters selected based on the observed values.. The more inferences are made, the more likely erroneous inferences become. Several statistical techniques have been developed to … granite and marble fabricatorsWebJul 22, 2015 · A graphical multiple testing procedure with "no-dead-end" provides an opportunity to fully recycle α across hypothesis families. Two hypothetical clinical trial examples are used to illustrate ... chingree插件WebNov 1, 2015 · We categorize multiple testing procedures for non-hierarchical hypotheses as “non-hierarchical” multiple testing procedures which include commonly used … ching rd 124ching rebecca s mdWebMany multiple testing procedures (MTP) have been developed in recent years. Among these new procedures, the graphical approach is flexible and easy to communicate with non-statisticians. A hypothetical Phase III clinical trial design is introduced in this manuscript to demonstrate how graphical approach can be applied in clinical product development. … granite and marble sales near me