High-affinity choline transporter 1
Web1 de jan. de 2024 · The high-affinity choline transporter was first cloned in 2000 and designated as CHT1 (Okuda et al. 2000 ). Structure and Functional Properties of CHT1 … WebAt high concentrations, choline is transported primarily by a low-affinity and Na + -independent system that is inhibited by hemicholinium-3 (HC3) 10 with a high Ki of …
High-affinity choline transporter 1
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WebHigh affinity choline transporter 1, Hemicholinium-3-sensitive choline transporter, CHT, Solute carrier family 5 member 7. eCl@ss: 32160702. NACRES: NA.41. Recommended Products. Slide 1 of 10. 1 of 10. Sigma-Aldrich. AV41516. Anti-SLC22A1 (AB1) antibody produced in rabbit. IgG fraction of antiserum. Web22 de jul. de 2024 · The first transporter is high-affinity choline transporter 1 (CHT1) that is expressed in cholinergic neurons and is linked to acetylcholine synthesis, which has a high affinity for choline. The second is organic cationic transporters OCT1 and OCT2 that have low affinity for choline, which recognize many cationic substances, and are mainly …
Web18 de fev. de 2024 · High-affinity choline transporter 1 (CHT1), which is mainly present on the presynaptic terminal and cytoplasm of cholinergic neurons, is involved in the … Web31 de out. de 2000 · Here we report the molecular cloning and functional characterization of the human high-affinity choline transporter (hCHT1). The hCHT1 exhibits significant …
Webcho-1 High-affinity choline transporter 1 [] Gene ID: 178274, updated on 22-Sep-2024 Summary Enables choline transmembrane transporter activity. Involved in choline … WebProtein target information for High affinity choline transporter 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay …
Web1 de mai. de 1990 · It is demonstrated that these two affinity states of [3H]HC‐3 binding are totally interconvertible; addition of 0.1 mM ATP in the binding assay medium …
WebPeroxynitrite donor SIN-1 modifies high-affinity choline transporter activity by modifying its intracellular trafficking Journal of Neuroscience April 18, 2012 Other ... how many gold gloves did al kaline winWeb1 de out. de 2014 · The high-affinity choline transporter (CHT) is the rate-limiting determinant of acetylcholine (ACh) synthesis, yet the transporter remains a largely undeveloped target for the detection and… Expand 15 PDF Competitive inhibition of the high-affinity choline transporter by tetrahydropyrimidine anthelmintics. houzz window shadesWeb1 de mai. de 1990 · It is demonstrated that these two affinity states of [3H]HC‐3 binding are totally interconvertible; addition of 0.1 mM ATP in the binding assay medium quantitatively converted all the binding sites to the low‐affinity state, whereas addition of 1 mM β,γ‐methylene 5′‐ATP quantitatively Conversion of all thebinding sites toThe … houzz white kitchensWebCHT1 is a member of the SLC5 family of solute transporters and is assigned to SLC5A7 ( 12. ). Its amino acid sequence has 20–25% homology with that of other members of this family ( 13. ). It has been assumed that all members of the family possess a common 13-transmembrane domain core ( 14. houzz window treatments kitchenWebThe molecular entity for the high-affinity choline transporter was identified and is designated CHT1, which mediates Na+- and Cl−-dependent choline uptake with high sensitivity to hemicholinium-3 and has been characterized both at the molecular and functional levels. The cholinergic neurons have long been a model for biochemical … houzz white shelvesWeb29 de jul. de 2014 · Highaffinity choline transporter 1 is involved in choline transport from the extracellular space to the neuron (48). Innexin 2 is required for the regulation of … houzz white medicine cabinetWebThe molecular entity for the high-affinity choline transporter was identified and is designated CHT1, which mediates Na+- and Cl−-dependent choline uptake with high … houzz window treatments modern fmaily rooms