Phip protein

Author: krcm

August undefined, 2024

WebbDetailed information about the celline expression of PHIP in Leukemia, AML stained with HPA019838. The antibody showed a Medium/High level of staining. Search: ... GENE/PROTEIN ANTIBODY/ANTIGEN CELL ATLAS HPA019838 LEUKEMIA, AML CELL ATLAS HPA019140 LEUKEMIA, AML Dictionary. WebbThe PHIP gene encodes at least 3 proteins, PHIP, PHIP1 (also known as DCAF14), and NDRP, through alternative splicing. DCAF14 acts as a substrate receptor in a ubiquitin …

PHIP gene variants with protein modeling, interactions, and …

WebbPHIP was initially identified through interactions with the pleckstrin homology domain of Insulin Receptor Signalling proteins, has been shown to mediate transcriptional … http://v13.proteinatlas.org/ENSG00000146247-PHIP/cell/HPA019838/Leukemia%2C+AML tier 1 schedule definition

PHIP gene variants with protein modeling, interactions, and …

Webb16 jan. 2024 · FIGURE 1.PHIP variants associated with Chung-Jansen syndrome identified in the present cohort and/or described in the literature (A) Schematic representation of PHIP exons (top; 1–40) and its encoded protein (bottom) showing the identified variants relative to the protein domains/regions. Variants identified in the present cohort are … Webb22 dec. 2000 · In contrast to full-length PHIP, overexpression of the PH-binding region of PHIP has a pronounced inhibitory effect on insulin-induced IRS-1 tyrosine phosphorylation levels. Furthermore, expression of this dominant-negative PHIP mutant leads to a marked attenuation of insulin-stimulated mitogen-activated protein kinase activity. WebbGENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human … the margin in economics

PHIPing along: Evolution of PHIP as a cancer biomarker and a …

UniProt

WebbExpression of PHIP (BRWD2, DCAF14, FLJ20705, ndrp, WDR11) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. WebbScore. PHIP. PH-interacting protein; Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti- apoptotic activity through … tier 1 security levelWebbExpression of PHIP (BRWD2, DCAF14, FLJ20705, ndrp, WDR11) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We … the margin in real estate is

"Webb5 okt. 2010 · PH-interacting protein Short names PHIP Alternative names DDB1- and CUL4-associated factor 14 IRS-1 PH domain-binding protein WD repeat-containing protein 11 Gene names Name PHIP Synonyms DCAF14, WDR11 Organism names Organism Homo … " - Phip protein

Phip protein

Immune cell - PHIP - The Human Protein Atlas

WebbPHIP is part of cluster 15 Non-specific - Protein binding with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore … Webb16 jan. 2024 · In 2016 and 2024, Chung, Jansen and others described a new syndrome caused by haploinsufficiency of PHIP (pleckstrin homology domain interacting protein, OMIM *612,870) and mainly characterized by ...

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Webb22 jan. 2024 · In order to construct a comprehensive library of allergenic proteins, the curated Allergome database 9 was downloaded from UniProt (accessed 6 August 2024) and used as input to the PhIP-Seq pepsyn ... WebbUseful information about the gene from Entrez. This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter tra …

Webb1 sep. 2024 · PHIP copy number was enriched in metastatic melanomas harboring mutant NRAS or expressing PTEN protein (cohort No. 2). PHIP copy number was significantly elevated in metastatic melanomas when compared with matched primary tumors from the same patient (cohort No. 3). Several of these associations were replicated using TCGA … Webb6 juni 2024 · PHF6 is chromatin-bound protein that recognizes histone methylation marks through its 2 PHD-like zinc finger domains, but it lacks enzymatic activity and it might …

WebbResponse surface optimization of effects of some processing variables on carcinogenicmutagenic heterocyclic aromatic amine (HAA) content in cooked patties WebbTitle: Qualitative and Quantitative Analysis of Heterocyclic Amines in Hot Processed Meat Products by SWATH® of X500R Subject: Heterocyclic Amines (HCAs) are one of the main hazards in the thermal processing of protein-rich food such as meat. hese substances can covalently combine with DNA to cause carcinogenesis and mutagenesis.

Webb5 mars 2024 · PHIP regulates expression of focal adhesion proteins and physically interacts with vinculin, mechanisms by which it promotes tumor cell motility and …

WebbVariants in the pleckstrin homology domain-interacting protein (PHIP) gene are implicated in the clinical phenotype of Chung-Jansen syndrome, which includes dysmorphic features, cognitive dysfunction, aberrant behavior, and childhood onset obesity. Following a systematic literature review, 35 patients are reported to have unique PHIP variants ... the margin is real estateWebbHeterocyclic amines (HCAs) are mutagenic and carcinogenic compounds found in cooked meat and fish. Although HCAs are known to form adducts with protein after metabolic activation, adduct formation during cooking has not been elucidated. In this study, we showed that 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) is released from … tier 1 scaled advice meaning tier 1 settings sa healthWebbPHIP protein name Recommended name PH-interacting protein Aliases BRWD2, DCAF14, DDB1 and CUL4 associated factor 14, FLJ20705, ndrp From Uniport PHIP Gene family … tier 1 rwf1011 water filterWebb13 nov. 2024 · Abstract. Variants in the pleckstrin homology domain-interacting protein ( PHIP) gene are implicated in the clinical phenotype of Chung–Jansen syndrome, which … tier 1 sex offender registration ohioWebbSubcellular - PHIP - The Human Protein Atlas SUMMARY TISSUE BRAIN SINGLE CELL TISSUE CELL PATHOLOGY DISEASE IMMUNE BLOOD SUBCELL CELL LINE PHIP … tier 1 rugby nationsWebb21 mars 2024 · anti-PIP antibody (Prolactin-Induced Protein) AA 1-146. Biorbyt antibodies for PIP. orb101264. orb102651. Boster Bio Antibodies for PIP. A04543. A04543-1. Boster … the margin of safety can be expressed as