WebNormally, Raji cells are doxorubicin-sensitive, but Raji cells cocultured with NK cells become doxorubicin-resistant. In addition, we detected the upregulation of CD69 and … Web12 de oct. de 2015 · In comparison to CIK and γδ T cells, the NK cells expanded in this study were significantly more cytotoxic toward many kinds of malignant cells lines including NK-resistant Raji cells (Fig. 6f). Raji cells normally elude NK cell recognition due to their expression of inhibitory KIR ligands (HLA-Cw3 and HLA-Cw4) and a lack of NKG2D …
NK cells converge lytic granules to promote cytotoxicity and …
Web26 de nov. de 2024 · The human natural killer (NK) cell line, NK-92, isolated from a patient with NK-cell lymphoma, is fully characterized, expandable with maintained cytotoxicity, and available as clinical... WebNK sensitivity does not develop in P3HR-1 superinfected Raji cells that are cultured in the presence of the RNA synthesis inhibitor actinomycin D and drops to half the amount … black white 3 colorblock jumpsuit harper rose
Membrane-Bound IL-21 Promotes Sustained - PLOS
Web6 de jun. de 2013 · In this study, the immuno-modulatory and anticancer activities of marine algae, Spirulina maxima grown in deep-sea water (DSW), were investigated. It was found that the extract of S. maxima, cultured in DSW, effectively suppressed the expression of Bcl2 in A549 cells as well as inhibiting various human cancer cells with concentration … Web24 de ago. de 2007 · Importantly, in contrast to parental NK-92, CD20-specific NK cells efficiently lysed CD20 expressing but otherwise NK-resistant established and primary lymphoma and leukemia cells, demonstrating that this strategy can overcome NK-cell resistance and might be suitable for the development of effective cell-based therapeutics … Web15 de dic. de 2011 · The prototypical NK-resistant RAJI cell is sensitive to NK-mediated lysis after priming through contact with CTV-1. Resting human NK cells were … black white 2 title screen